5 Best Anti-Inflammatory Creams Over The Counter

Inflammation can be the source of immense pain and anyone who has experienced this discomfort will certainly agree. Whether it be from arthritis, sore muscles,  joint pain, fibromyalgia or any other inflammation induced condition, the pain puts a damper on your life. Fortunately, there are numerous anti-inflammatory creams over the counter you can buy to reduce inflammation and lessen pain.

The only problem is that some products are effective, while others simply don’t work as advertised.

To make things easier for you, listed here are the top 5 best anti-inflammatory creams on the market.

Where to Buy
SynthaFlex | 4 Oz. - Best Anti-Inflammatory Cream - Joint Pain and Inflammation Cream - Arthritis
Biofreeze Arthritis Pain Relief Gel, Fast Acting, Long Lasting, & Powerful Topical Pain Reliever, 4 oz
Topricin Pain Relief Therapy Cream (8 oz) Fast Acting Pain Relieving Rub
Outback Pain Relief Roll-On Oil 50mL (1.69 fl oz) - All Natural Topical Oil Pain Reliever
Penetrex Joint & Muscle Therapy, 2 Oz Cream – Intensive Concentrate for Relief & Recovery


1. Synthaflex Joint Relief Cream


SynthaFlex is great for treating any conditions that cause nerve pain, joint pain, and soreness. This particular cream proudly uses almost all natural ingredients. Thus, the potency of the cream has a powerful anti-inflammatory effect.

SynthaFlex contains Celadrin, a patented substance made up of cetylated fatty acid esters. This formula’s properties allow it to reduce inflammation in order to relieve pain and improve mobility.

Since the cream is topical, your top layer of skin absorbs the substance initially. From there the cream can rejuvenate synovial fluids that support bones and joints. As a result, the cream promotes flexibility as joint inflammation decreases.

This particular cream is also known for a study involving SynthaFlex’s key ingredient. There was a double-blind study at the University of Connecticut where every single subject tested with Celadrin showed decreased joint inflammation and improved joint mobility in under 30 minutes. Qualities such as flexibility, muscle endurance, and pain levels were studied among participants. Upon more frequent use of the substance, their conditions improved.

In turn, SynthaFlex Joint Relief Cream is one of the best over the counter anti-inflammatory creams.

To See SynthaFlex Joint Pain and Inflammation Cream Price On Amazon Click Here! 

2. Biofreeze Pain Relief Gel

Biofreeze-Pain-Relief-GelBiofreeze Pain Relief Gel is great for joint pains such as arthritis as well as common joint and muscle pains that come from exercise. The product claims to be the number 1 clinically used and recommended topical analgesic.

Biofreeze is also widely used by professionals in the fitness industry for exercise-related pains and discomforts. Chiropractors, massage therapists, athletic trainers, podiatrists, and physical therapist commonly use Biofreeze for fast relief for their clients. If you exercise a good amount or are prone to physical labor at your job, this particular cream would be worthwhile to try.

Priding its self in the fantastic quality of ingredients, Biofreeze is known to use natural and powerful concoctions of natural extracts. The formula is free of parabens and propylene glycol as it is made with USP grade ingredients as well.

Upon application, the cream penetrates the dermis and deeply relieves the stressed muscles and joints below.

To See Biofreeze Pain Relief Gel Price on Amazon Price Click Here!

3. Topricin Pain Relief Therapy Cream

Topricin Pain Relief Therapy Cream (8 oz) Fast Acting Pain Relieving Rub

Topricin Pain Relief Therapy Cream is by far one of the most versatile anti-inflammatory creams over the counter. It can be used for tendinitis, leg cramps, heel spurs, back pain, soreness and just about everything in-between.

There are 11 natural bio-medicines that make up Topricin which is why it is so versatile, to begin with. Each bio-medicine is designed to treat one particular aspect of inflammation and soreness in order to aid the healing process as effectively and efficiently as possible.

The product also is great because it has very few side effects. Topricin pain relief therapy cream does not have any side effects that will interfere with other medications and as a result, it is a great alternative for people who cannot take OTC oral pain medications.

The ingredients are of the utmost quality as well. Made in the USA, there are no real fillers are additives that will dilute the potency of the active ingredients.

To See Topricin Pain Relief Therapy Cream Price On Amazon Click Here!

4. Outback Pain Relief

Outback Pain Relief Roll-On Oil 50mL (1.69 fl oz) - All Natural Topical Oil Pain Reliever

Outback Pain Relief is another versatile over the counter anti-inflammatory cream for all aches, pains, and soreness. The product prides its self on harvesting the most potent extracts that the luscious Australian habitat has to offer.

Outback Pain Relief surprisingly only consists of 5 ingredients which include Australian tea tree oil, blue mallee, eucalyptus oil, olive oil, and vanilla. These 5 ingredients when used in conjunction create a powerful bond that gives Outback Pain Relief its edge.

This particular cream is also known to provide nonstop relief for hours on end. However, most products only last for an hour or so but then their effects begin to die off. Outback Pain Relief, on the other hand, can leave you feeling relieved for the beginning of the day to the end.

To apply the stick simply rub the stick on the inflamed area until the gel covers the aggravated area. From there, you may massage the mixture into the skin until it becomes absorbed.

To See Outback All-Natural Pain Relief Price On Amazon Click Here!

5. Penetrex Pain Relief Therapy- Best Anti-Inflammatory Cream Over The Counter


Penetrex Pain Relief Therapy is likely the best anti-inflammatory cream over the counter today.

The formula is so effective in fact that many companies try to emulate it. You can use Penetrex for inflamed muscles, ligaments, tendons and joints.

This cream is unique since you can use less of it as your condition improves. As you continue to use the cream, over time you need fewer and fewer applications as the relief becomes more permanent from frequent use. Users report this effect as more “efficient relief” relative to other products of its kind.

To apply the cream, take an appropriate scoop out of the container and massage the cream into your skin until it is completely absorbed into the skin. You will begin to feel the effects soon after.

There is also a 100 percent money back guarantee policy if it so happens to not work for you.

To See Penetrex Pain Relief Therapy Price On Amazon Click Here!

In conclusion, these are the best anti-inflammatory creams over the counter today. Thanks for reading!

For more information on the top anti-inflammatory agents click here!